If someone is suffering from malaria, the drug is only one quinine. Healing substances in it has been recognized and used for decades. Is quinine only plants that can cope with illnesses caused by mosquitoes carrying Plasmodium?
Researchers at the Institute of Tropical Disease, Airlangga University apparently has worked more than ten years of searching for drugs other than quinine. Such efforts increasingly see a bright spot, even some people believe more potent than quinine.
Researchers at the Institute of Tropical Disease, Airlangga University apparently has worked more than ten years of searching for drugs other than quinine. Such efforts increasingly see a bright spot, even some people believe more potent than quinine.
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| weus.net |
Cempedak nut shell, this is the source of the malaria drug invented by the scientists in Surabaya. The researchers used the bark Cempedak that only comes from Borneo. "Selected from Kalimantan, because in this region is the most superior kind," ata Research Team Leader of Anti-Malaria Drugs ITD-Aty Widyawaruyanti Airlangga University Dr., MSc.
Bark plant with the Latin name Artocarpus champedem are processed into the extract has clinically tested a group of compounds that can kill malaria parasites.
"There are some compounds that our isolation and testing. One of the more active of the Kina," said Aty.
Because it is more active, known compounds named Heteroflavanon C, said Aty, has compounds that are superior compared with quinine.
Test Samples
Bark plant with the Latin name Artocarpus champedem are processed into the extract has clinically tested a group of compounds that can kill malaria parasites.
"There are some compounds that our isolation and testing. One of the more active of the Kina," said Aty.
Because it is more active, known compounds named Heteroflavanon C, said Aty, has compounds that are superior compared with quinine.
Test Samples
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| Cempedak tree, a drug candidate for malaria / ciputranews.com |
"The results of clinical trials are still ongoing to 60 people," said Aty, adding that this is the second phase to be skipped.
Of the four phases, the researchers had passed the first phase of which is a toxic phase, which aims to see the toxicity to the subject.
"But for the herbal medicine immediately jump to the trial to the sick," said Aty.
Meanwhile, for the third and fourth phase is done when the drug was introduced to the market.
Sixty of these patients taking anti-malaria drug from the bark Cempedak every day for five days at a dose of 450 milligrams.
"After five days of consumption, the patient claimed to feel more comfortable because they do not feel the fever, no chills, and headache," said Aty.
On the fifth day the patient's condition re-examined and the malaria parasite was found to be negative. However Aty explained that this condition will continue to be monitored until the twentieth day.
Formulas already getting a patent is said Aty already got an offer to be marketed by the industry, but have not found an agreement.
Of the four phases, the researchers had passed the first phase of which is a toxic phase, which aims to see the toxicity to the subject.
"But for the herbal medicine immediately jump to the trial to the sick," said Aty.
Meanwhile, for the third and fourth phase is done when the drug was introduced to the market.
Sixty of these patients taking anti-malaria drug from the bark Cempedak every day for five days at a dose of 450 milligrams.
"After five days of consumption, the patient claimed to feel more comfortable because they do not feel the fever, no chills, and headache," said Aty.
On the fifth day the patient's condition re-examined and the malaria parasite was found to be negative. However Aty explained that this condition will continue to be monitored until the twentieth day.
Formulas already getting a patent is said Aty already got an offer to be marketed by the industry, but have not found an agreement.
Sources:
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